RT-3 20mg (GLP-3)
Synthetic peptide with triple agonist receptor activity Standard 20mg research quantity for multi-receptor pathway studies 99% pure () · Lyophilized powder For in vitro receptor interaction studies only
For laboratory research use only. Not for human or veterinary consumption. SKU RT20.
Product details.
What the third receptor adds
The glucagon receptor is the differentiator. Sema (GLP-1 only) and TZ-2 (GLP-1 + GIP) leave it untouched. But glucagon receptor activation drives energy expenditure through hepatic and thermogenic pathways that neither GLP-1 nor GIP can access. Preclinical data shows that adding this third receptor target to the dual GIP/GLP-1 framework produces the most pronounced effects on metabolic parameters of any approach studied to date.
All three receptors are G-protein coupled and signal through cAMP/PKA cascades, but their tissue distribution and downstream effects are distinct. GLP-1 receptors dominate in the pancreas and hypothalamus. GIP receptors are concentrated in adipose tissue and the CNS. Glucagon receptors are heavily expressed in the liver. RT-3 reaches all three tissue compartments.
Specifications
| Classification | Triple GLP-1/GIP/Glucagon receptor agonist |
| Form | Lyophilized powder |
| Quantity | 20mg per vial |
The incretin ladder: Sema vs TZ-2 vs RT-3
Heritage Labs USA stocks all three tiers. Sema is the selective GLP-1 agonist (31 amino acids, one receptor). TZ-2 is the dual GIP/GLP-1 agonist (39 amino acids, two receptors). RT-3 is the triple agonist (three receptors). Comparative preclinical literature documents a clear stepwise increase in metabolic parameter engagement as you move from single to dual to triple activation.
Frequently paired with
- Cagri 5mg — Hindbrain satiety pathway via amylin receptors
- MOTS-C 10mg — AMPK-mediated metabolic signaling
- NAD+ 500mg — Cellular energy metabolism and sirtuin pathways
Storage
- Lyophilized: -20°C for long-term stability
- Reconstituted: 2-8°C, use within 30 days
For laboratory research use only. Not for human or veterinary use.
Technical reference adapted from the original Heritage Labs USA product listing. This description is not a certificate of analysis or evidence of testing for inventory supplied by this store.
