Semax 5mg
ACTH(4-10) fragment analog heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) with PGP stabilization 100+ published studies — retains neurotrophic activity without steroidogenic effects Research-grade · CAS 80714-61-0 For in vitro neuropeptide research only
For laboratory research use only. Not for human or veterinary consumption. SKU XA5.
Product details.
Specifications
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro (ACTH 4-10 + PGP) |
| Amino Acids | 7 |
| Molecular Formula | C39H63N11O10 |
| Molecular Weight | 813.97 g/mol |
| CAS Number | 80714-61-0 |
| Form | Lyophilized powder |
| Quantity | 5mg per vial |
Neurotrophic factor effects
Research has documented Semax’s influence on BDNF, NGF, and GDNF expression in neuronal cultures. The interesting part is what it does not do: unlike the full ACTH molecule, the 4-10 fragment does not drive adrenal steroid production. The neurotrophic activity and steroidogenic activity occupy different regions of the parent peptide, and Semax retains only the former.
Additional research areas
Published studies have examined dopaminergic and serotonergic system modulation, oxidative stress markers in neuronal models, and the pharmacokinetic properties of the Pro-Gly-Pro stability extension — a design shared with the related peptide Selank (tuftsin + PGP).
Frequently paired with
- Selank 5mg — Both share the PGP stabilization motif but derive from different parent sequences.
Storage
- Lyophilized: -20°C
- Reconstituted: 2-8°C, use within 30 days
For laboratory research use only. Not for human or veterinary use.
Technical reference adapted from the original Heritage Labs USA product listing. This description is not a certificate of analysis or evidence of testing for inventory supplied by this store.
