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Heritage Labs USA
TB-500 Capsules
• Research grade
Capsules

TB-500 Capsules

Synthetic Thymosin Beta-4 — all 43 amino acids with the LKKTETQ actin-binding motif Oral capsule format — 500 mcg per capsule, 30 capsules per bottle, no reconstitution CAS 77591-33-4 For in vitro cell-migration and actin research only

$66.99• In stock
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▤Batch-specific test documentation is not currently linked to this product.

For laboratory research use only. Not for human or veterinary consumption. SKU TB500C.

OVERVIEW

Product details.

An oral capsule format

The peptides in this category are most often supplied as lyophilized powder for reconstitution. This listing supplies TB-500 as a pre-measured oral capsule instead — each capsule holds a fixed 500 mcg, so researchers can standardize per-capsule quantities without reconstitution, vials, or measuring. It is the same synthetic 43-amino-acid Thymosin Beta-4 sequence as the vial presentation; only the delivery format differs.

Specifications

Full Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Active Region LKKTETQ (amino acids 17-23)
Molecular Formula C212H350N56O78S
Molecular Weight 4963.44 g/mol
CAS Number 77591-33-4
PubChem CID 16132042
Form Oral capsule
Strength 500 mcg per capsule
Format 30 capsules per bottle

The research record

Malinda et al. reported a 41% increase in re-epithelialization within 4 days in full-thickness dermal wound models, concluding that “Tβ4 is a potent wound healing factor with multiple activities” (J Investigative Dermatology, 1999; PubMed 10469335).

Bock-Marquette et al. published findings in Nature showing enhanced cardiomyocyte migration and survival through integrin-linked kinase (ILK) and Akt signaling activation in myocardial infarction models (Nature, 2004; PubMed 15565145).

Philp et al. characterized angiogenesis and directional cell migration in both normal and aged rodent models through endothelial tube formation and ECM remodeling (Annals NYAS, 2004; PubMed 15037013).

Goldstein et al. reviewed NF-κB signaling modulation, pro-inflammatory cytokine reduction, and decreased inflammatory cell infiltration in tissue models (Expert Opinion on Biological Therapy, 2012; PubMed 22074294).

TB-500 vs BPC-157

Different mechanisms for different systems. TB-500 research centers on actin regulation, cell migration, blood vessel formation, and cardiac tissue. BPC-157 research centers on gastrointestinal integrity, connective tissue, and nitric oxide pathways. Published protocols regard them as complementary, not interchangeable. Heritage Labs USA carries both in capsule and vial formats.

Research applications

  • Cell migration and wound closure assays
  • Actin polymerization dynamics and G-actin/F-actin equilibrium
  • Angiogenesis pathway screening
  • ECM remodeling and collagen expression
  • Inflammatory signaling profiling
  • Cardiac cell survival and ILK activation

Frequently paired with

Storage

  • Sealed capsules: Store in a cool, dry place away from light and moisture.
  • Handling: Keep the bottle tightly closed; avoid heat and humidity.
  • No reconstitution required.

References

  1. Malinda KM, et al. J Investigative Dermatology. 1999;113(3):364-368. PubMed 10469335
  2. Bock-Marquette I, et al. Nature. 2004;432(7016):466-472. PubMed 15565145
  3. Philp D, et al. Annals NYAS. 2004;1012:44-52. PubMed 15037013
  4. Goldstein AL, et al. Expert Opinion on Biological Therapy. 2012;12(1):37-51. PubMed 22074294

Third-party lab tested · For research use only. Not for human consumption.

Technical reference adapted from the original Heritage Labs USA product listing. This description is not a certificate of analysis or evidence of testing for inventory supplied by this store.

For laboratory research use only. Not for human or veterinary consumption.